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Cell shape, and not 2D migration, predicts extracellular matrix-driven 3D cell invasion in breast cancer

Metastasis, the leading cause of death in cancer patients, requires the invasion of tumor cells through the stroma in response to migratory cues, in part provided by the extracellular matrix (ECM). Recent advances in proteomics have led to the identification of hundreds of ECM proteins, which are mo...

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Detalles Bibliográficos
Autores principales: Baskaran, Janani P., Weldy, Anna, Guarin, Justinne, Munoz, Gabrielle, Shpilker, Polina H., Kotlik, Michael, Subbiah, Nandita, Wishart, Andrew, Peng, Yifan, Miller, Miles A., Cowen, Lenore, Oudin, Madeleine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202897/
https://www.ncbi.nlm.nih.gov/pubmed/32455252
http://dx.doi.org/10.1063/1.5143779