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Cell shape, and not 2D migration, predicts extracellular matrix-driven 3D cell invasion in breast cancer
Metastasis, the leading cause of death in cancer patients, requires the invasion of tumor cells through the stroma in response to migratory cues, in part provided by the extracellular matrix (ECM). Recent advances in proteomics have led to the identification of hundreds of ECM proteins, which are mo...
Autores principales: | Baskaran, Janani P., Weldy, Anna, Guarin, Justinne, Munoz, Gabrielle, Shpilker, Polina H., Kotlik, Michael, Subbiah, Nandita, Wishart, Andrew, Peng, Yifan, Miller, Miles A., Cowen, Lenore, Oudin, Madeleine J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AIP Publishing LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7202897/ https://www.ncbi.nlm.nih.gov/pubmed/32455252 http://dx.doi.org/10.1063/1.5143779 |
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