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Microrheology for Hi-C Data Reveals the Spectrum of the Dynamic 3D Genome Organization

The one-dimensional information of genomic DNA is hierarchically packed inside the eukaryotic cell nucleus and organized in a three-dimensional (3D) space. Genome-wide chromosome conformation capture (Hi-C) methods have uncovered the 3D genome organization and revealed multiscale chromatin domains o...

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Detalles Bibliográficos
Autores principales: Shinkai, Soya, Sugawara, Takeshi, Miura, Hisashi, Hiratani, Ichiro, Onami, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203008/
https://www.ncbi.nlm.nih.gov/pubmed/32191860
http://dx.doi.org/10.1016/j.bpj.2020.02.020