Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function

Heterochromatin in the eukaryotic genome is rigorously controlled by the concerted action of protein factors and RNAs. Here, we investigate the RNA binding function of ATRX, a chromatin remodeler with roles in silencing of repetitive regions of the genome and in recruitment of the polycomb repressiv...

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Detalles Bibliográficos
Autores principales: Ren, Wenqing, Medeiros, Nicole, Warneford-Thomson, Robert, Wulfridge, Phillip, Yan, Qingqing, Bian, Joyce, Sidoli, Simone, Garcia, Benjamin A., Skordalakes, Emmanuel, Joyce, Eric, Bonasio, Roberto, Sarma, Kavitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203109/
https://www.ncbi.nlm.nih.gov/pubmed/32376827
http://dx.doi.org/10.1038/s41467-020-15902-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203109/
https://www.ncbi.nlm.nih.gov/pubmed/32376827
http://dx.doi.org/10.1038/s41467-020-15902-9

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