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Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function
Heterochromatin in the eukaryotic genome is rigorously controlled by the concerted action of protein factors and RNAs. Here, we investigate the RNA binding function of ATRX, a chromatin remodeler with roles in silencing of repetitive regions of the genome and in recruitment of the polycomb repressiv...
Autores principales: | Ren, Wenqing, Medeiros, Nicole, Warneford-Thomson, Robert, Wulfridge, Phillip, Yan, Qingqing, Bian, Joyce, Sidoli, Simone, Garcia, Benjamin A., Skordalakes, Emmanuel, Joyce, Eric, Bonasio, Roberto, Sarma, Kavitha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203109/ https://www.ncbi.nlm.nih.gov/pubmed/32376827 http://dx.doi.org/10.1038/s41467-020-15902-9 |
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