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Multiparametric Mechanistic Profiling of Inotropic Drugs in Adult Human Primary Cardiomyocytes

Effects of non-cardiac drugs on cardiac contractility can lead to serious adverse events. Furthermore, programs aimed at treating heart failure have had limited success and this therapeutic area remains a major unmet medical need. The challenges in assessing drug effect on cardiac contractility poin...

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Detalles Bibliográficos
Autores principales: Abi-Gerges, Najah, Indersmitten, Tim, Truong, Ky, Nguyen, William, Ratchada, Phachareeya, Nguyen, Nathalie, Page, Guy, Miller, Paul E., Ghetti, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203129/
https://www.ncbi.nlm.nih.gov/pubmed/32376974
http://dx.doi.org/10.1038/s41598-020-64657-2