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Multiparametric Mechanistic Profiling of Inotropic Drugs in Adult Human Primary Cardiomyocytes
Effects of non-cardiac drugs on cardiac contractility can lead to serious adverse events. Furthermore, programs aimed at treating heart failure have had limited success and this therapeutic area remains a major unmet medical need. The challenges in assessing drug effect on cardiac contractility poin...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203129/ https://www.ncbi.nlm.nih.gov/pubmed/32376974 http://dx.doi.org/10.1038/s41598-020-64657-2 |