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Structural and mechanical remodeling of the cytoskeleton maintains tensional homeostasis in 3D microtissues under acute dynamic stretch

When stretched, cells cultured on 2D substrates share a universal softening and fluidization response that arises from poorly understood remodeling of well-conserved cytoskeletal elements. It is known, however, that the structure and distribution of the cytoskeleton is profoundly influenced by the d...

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Detalles Bibliográficos
Autores principales: Walker, Matthew, Rizzuto, Pauline, Godin, Michel, Pelling, Andrew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203149/
https://www.ncbi.nlm.nih.gov/pubmed/32376876
http://dx.doi.org/10.1038/s41598-020-64725-7