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Rational identification and characterisation of peptide ligands for targeting polysialic acid

The alpha-2,8-linked form of the polysaccharide polysialic acid (PSA) has widespread implications in physiological and pathological processes, ranging from neurological development to disease progression. Though the high electronegativity and excluded volume of PSA often promotes interference of bio...

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Detalles Bibliográficos
Autores principales: Shastry, Divya G., Irudayanathan, Flaviyan Jerome, Williams, Asher, Koffas, Mattheos, Linhardt, Robert J., Nangia, Shikha, Karande, Pankaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203153/
https://www.ncbi.nlm.nih.gov/pubmed/32376914
http://dx.doi.org/10.1038/s41598-020-64088-z