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Platelet Toll-Like Receptors Mediate Thromboinflammatory Responses in Patients With Essential Thrombocythemia

Essential thrombocythemia (ET) is comprised among chronic myeloproliferative neoplasms (MPN) and is caused by driver mutations in JAK2, CALR, and MPL, which lead to megakaryocyte proliferation and prominent thrombocytosis. Thrombosis remains the main cause of morbidity in ET and is driven by the int...

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Detalles Bibliográficos
Autores principales: Marín Oyarzún, Cecilia P., Glembotsky, Ana C., Goette, Nora P., Lev, Paola R., De Luca, Geraldine, Baroni Pietto, María C., Moiraghi, Beatriz, Castro Ríos, Miguel A., Vicente, Angeles, Marta, Rosana F., Schattner, Mirta, Heller, Paula G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203216/
https://www.ncbi.nlm.nih.gov/pubmed/32425934
http://dx.doi.org/10.3389/fimmu.2020.00705