Lacosamide intake during pregnancy increases the incidence of foetal malformations and symptoms associated with schizophrenia in the offspring of mice

The use of first and second generation antiepileptic drugs during pregnancy doubles the risk of major congenital malformations and other teratogenic defects. Lacosamide (LCM) is a third-generation antiepileptic drug that interacts with collapsing response mediator protein 2, a protein that has been...

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Detalles Bibliográficos
Autores principales: López-Escobar, Beatriz, Fernández-Torres, Rut, Vargas-López, Viviana, Villar-Navarro, Mercedes, Rybkina, Tatyana, Rivas-Infante, Eloy, Hernández-Viñas, Ayleen, Álvarez del Vayo, Concepción, Caro-Vega, José, Sánchez-Alcázar, José A., González-Meneses, Antonio, Carrión, M. Ángel, Ybot-González, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203245/
https://www.ncbi.nlm.nih.gov/pubmed/32376856
http://dx.doi.org/10.1038/s41598-020-64626-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203245/
https://www.ncbi.nlm.nih.gov/pubmed/32376856
http://dx.doi.org/10.1038/s41598-020-64626-9

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