Anti-Inflammatory and Anti-Nociceptive Effects of Cocoa: A Review on Future Perspectives in Treatment of Pain

Cocoa has been reported to have medicinal properties. It contains a wide range of phytochemicals, including polyphenols, which have been shown to exert anti-inflammatory and antioxidant actions, and also to have a positive effect on pain. Other components of cocoa might be able to positively influen...

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Autores principales: De Feo, Martina, Paladini, Antonella, Ferri, Claudio, Carducci, Augusto, Del Pinto, Rita, Varrassi, Giustino, Grassi, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203300/
https://www.ncbi.nlm.nih.gov/pubmed/32314320
http://dx.doi.org/10.1007/s40122-020-00165-5
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author De Feo, Martina
Paladini, Antonella
Ferri, Claudio
Carducci, Augusto
Del Pinto, Rita
Varrassi, Giustino
Grassi, Davide
author_facet De Feo, Martina
Paladini, Antonella
Ferri, Claudio
Carducci, Augusto
Del Pinto, Rita
Varrassi, Giustino
Grassi, Davide
author_sort De Feo, Martina
collection PubMed
description Cocoa has been reported to have medicinal properties. It contains a wide range of phytochemicals, including polyphenols, which have been shown to exert anti-inflammatory and antioxidant actions, and also to have a positive effect on pain. Other components of cocoa might be able to positively influence pain perception through various mechanisms. Despite encouraging results from preclinical studies, there is a lack of evidence of antinociceptive effects of cocoa from clinical trials in humans. Further research is needed to better identify the active principles in cocoa, to understand the underlying mechanisms of action, and to establish efficacy in humans.
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spelling pubmed-72033002020-05-12 Anti-Inflammatory and Anti-Nociceptive Effects of Cocoa: A Review on Future Perspectives in Treatment of Pain De Feo, Martina Paladini, Antonella Ferri, Claudio Carducci, Augusto Del Pinto, Rita Varrassi, Giustino Grassi, Davide Pain Ther Review Cocoa has been reported to have medicinal properties. It contains a wide range of phytochemicals, including polyphenols, which have been shown to exert anti-inflammatory and antioxidant actions, and also to have a positive effect on pain. Other components of cocoa might be able to positively influence pain perception through various mechanisms. Despite encouraging results from preclinical studies, there is a lack of evidence of antinociceptive effects of cocoa from clinical trials in humans. Further research is needed to better identify the active principles in cocoa, to understand the underlying mechanisms of action, and to establish efficacy in humans. Springer Healthcare 2020-04-20 2020-06 /pmc/articles/PMC7203300/ /pubmed/32314320 http://dx.doi.org/10.1007/s40122-020-00165-5 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Review
De Feo, Martina
Paladini, Antonella
Ferri, Claudio
Carducci, Augusto
Del Pinto, Rita
Varrassi, Giustino
Grassi, Davide
Anti-Inflammatory and Anti-Nociceptive Effects of Cocoa: A Review on Future Perspectives in Treatment of Pain
title Anti-Inflammatory and Anti-Nociceptive Effects of Cocoa: A Review on Future Perspectives in Treatment of Pain
title_full Anti-Inflammatory and Anti-Nociceptive Effects of Cocoa: A Review on Future Perspectives in Treatment of Pain
title_fullStr Anti-Inflammatory and Anti-Nociceptive Effects of Cocoa: A Review on Future Perspectives in Treatment of Pain
title_full_unstemmed Anti-Inflammatory and Anti-Nociceptive Effects of Cocoa: A Review on Future Perspectives in Treatment of Pain
title_short Anti-Inflammatory and Anti-Nociceptive Effects of Cocoa: A Review on Future Perspectives in Treatment of Pain
title_sort anti-inflammatory and anti-nociceptive effects of cocoa: a review on future perspectives in treatment of pain
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203300/
https://www.ncbi.nlm.nih.gov/pubmed/32314320
http://dx.doi.org/10.1007/s40122-020-00165-5
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