Sirtuin 1 Inhibiting Thiocyanates (S1th)—A New Class of Isotype Selective Inhibitors of NAD(+) Dependent Lysine Deacetylases

Sirtuin 1 (Sirt1) is a NAD(+) dependent lysine deacetylase associated with the pathogenesis of various diseases including cancer. In many cancer types Sirt1 expression is increased and higher levels have been associated with metastasis and poor prognosis. However, it was also shown, that Sirt1 can h...

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Detalles Bibliográficos
Autores principales: Wössner, Nathalie, Alhalabi, Zayan, González, Jessica, Swyter, Sören, Gan, Jin, Schmidtkunz, Karin, Zhang, Lin, Vaquero, Alejandro, Ovaa, Huib, Einsle, Oliver, Sippl, Wolfgang, Jung, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203344/
https://www.ncbi.nlm.nih.gov/pubmed/32426286
http://dx.doi.org/10.3389/fonc.2020.00657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203344/
https://www.ncbi.nlm.nih.gov/pubmed/32426286
http://dx.doi.org/10.3389/fonc.2020.00657

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