Tetanus Toxin cis-Loop Contributes to Light-Chain Translocation

The clostridial neurotoxins (CNTs) comprise tetanus toxin (TT) and botulinum neurotoxin (BoNT [BT]) serotypes (A to G and X) and several recently identified CNT-like proteins, including BT/En and the mosquito BoNT-like toxin Pmp1. CNTs are produced as single proteins cleaved to a light chain (LC) an...

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Detalles Bibliográficos
Autores principales: Zuverink, Madison, Bluma, Matthew, Barbieri, Joseph T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203457/
https://www.ncbi.nlm.nih.gov/pubmed/32376703
http://dx.doi.org/10.1128/mSphere.00244-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203457/
https://www.ncbi.nlm.nih.gov/pubmed/32376703
http://dx.doi.org/10.1128/mSphere.00244-20

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