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Drosophila OTK Is a Glycosaminoglycan-Binding Protein with High Conformational Flexibility
The transmembrane protein OTK plays an essential role in plexin and Wnt signaling during Drosophila development. We have determined a crystal structure of the last three domains of the OTK ectodomain and found that OTK shows high conformational flexibility resulting from mobility at the interdomain...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203548/ https://www.ncbi.nlm.nih.gov/pubmed/32187531 http://dx.doi.org/10.1016/j.str.2020.02.008 |