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The hydroxypropyl‐β‐cyclodextrin‐minoxidil inclusion complex improves the cardiovascular and proliferative adverse effects of minoxidil in male rats: Implications in the treatment of alopecia

The efficacy of minoxidil (MXD) ethanolic solutions (1%‐5% w/v) in the treatment of androgenetic alopecia is limited by adverse reactions. The toxicological effects of repeated topical applications of escalating dose (0.035%‐3.5% w/v) and of single and twice daily doses (3.5% w/v) of a novel hydroxy...

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Detalles Bibliográficos
Autores principales: Maqoud, Fatima, Zizzo, Nicola, Mele, Antonietta, Denora, Nunzio, Passantino, Giuseppe, Scala, Rosa, Cutrignelli, Annalisa, Tinelli, Antonella, Laquintana, Valentino, la Forgia, Flavia, Fontana, Sergio, Franco, Massimo, Lopedota, Angela Assunta, Tricarico, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203570/
https://www.ncbi.nlm.nih.gov/pubmed/32378360
http://dx.doi.org/10.1002/prp2.585