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LAMPA, LArge Multidomain Protein Annotator, and its application to RNA virus polyproteins

MOTIVATION: To facilitate accurate estimation of statistical significance of sequence similarity in profile–profile searches, queries should ideally correspond to protein domains. For multidomain proteins, using domains as queries depends on delineation of domain borders, which may be unknown. Thus,...

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Detalles Bibliográficos
Autores principales: Gulyaeva, Anastasia A, Sigorskih, Andrey I, Ocheredko, Elena S, Samborskiy, Dmitry V, Gorbalenya, Alexander E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203729/
https://www.ncbi.nlm.nih.gov/pubmed/32003788
http://dx.doi.org/10.1093/bioinformatics/btaa065