MODER2: first-order Markov modeling and discovery of monomeric and dimeric binding motifs

MOTIVATION: Position-specific probability matrices (PPMs, also called position-specific weight matrices) have been the dominating model for transcription factor (TF)-binding motifs in DNA. There is, however, increasing recent evidence of better performance of higher order models such as Markov model...

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Detalles Bibliográficos
Autores principales: Toivonen, Jarkko, Das, Pratyush K, Taipale, Jussi, Ukkonen, Esko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203737/
https://www.ncbi.nlm.nih.gov/pubmed/31999322
http://dx.doi.org/10.1093/bioinformatics/btaa045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203737/
https://www.ncbi.nlm.nih.gov/pubmed/31999322
http://dx.doi.org/10.1093/bioinformatics/btaa045

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