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MODER2: first-order Markov modeling and discovery of monomeric and dimeric binding motifs
MOTIVATION: Position-specific probability matrices (PPMs, also called position-specific weight matrices) have been the dominating model for transcription factor (TF)-binding motifs in DNA. There is, however, increasing recent evidence of better performance of higher order models such as Markov model...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203737/ https://www.ncbi.nlm.nih.gov/pubmed/31999322 http://dx.doi.org/10.1093/bioinformatics/btaa045 |