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Dual-Luciferase-Based Fast and Sensitive Detection of Malaria Hypnozoites for the Discovery of Antirelapse Compounds

[Image: see text] Efforts to eradicate Plasmodium vivax malaria are hampered by the presence of hypnozoites, persisting stages in the liver that can reactivate after prolonged periods of time enabling further transmission and causing renewed disease. Large-scale drug screening is needed to identify...

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Detalles Bibliográficos
Autores principales: Voorberg-van der Wel, Annemarie M., Zeeman, Anne-Marie, Nieuwenhuis, Ivonne G., van der Werff, Nicole M., Klooster, Els J., Klop, Onny, Vermaat, Lars C., Kocken, Clemens H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203758/
https://www.ncbi.nlm.nih.gov/pubmed/32267675
http://dx.doi.org/10.1021/acs.analchem.0c00547