Cargando…

Dual-Luciferase-Based Fast and Sensitive Detection of Malaria Hypnozoites for the Discovery of Antirelapse Compounds

[Image: see text] Efforts to eradicate Plasmodium vivax malaria are hampered by the presence of hypnozoites, persisting stages in the liver that can reactivate after prolonged periods of time enabling further transmission and causing renewed disease. Large-scale drug screening is needed to identify...

Descripción completa

Detalles Bibliográficos
Autores principales:	Voorberg-van der Wel, Annemarie M., Zeeman, Anne-Marie, Nieuwenhuis, Ivonne G., van der Werff, Nicole M., Klooster, Els J., Klop, Onny, Vermaat, Lars C., Kocken, Clemens H. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203758/ https://www.ncbi.nlm.nih.gov/pubmed/32267675 http://dx.doi.org/10.1021/acs.analchem.0c00547

Ejemplares similares

A dual fluorescent Plasmodium cynomolgi reporter line reveals in vitro malaria hypnozoite reactivation
por: Voorberg-van der Wel, Annemarie M., et al.
Publicado: (2020)

Transgenic Fluorescent Plasmodium cynomolgi Liver Stages Enable Live Imaging and Purification of Malaria Hypnozoite-Forms
por: Voorberg-van der Wel, Annemarie, et al.
Publicado: (2013)

Sterile protection against relapsing malaria with a single-shot vaccine
por: Pasini, Erica M., et al.
Publicado: (2022)

Modeling Relapsing Malaria: Emerging Technologies to Study Parasite-Host Interactions in the Liver
por: Voorberg-van der Wel, Annemarie, et al.
Publicado: (2021)

Transfection Models to Investigate Plasmodium vivax-Type Dormant Liver Stage Parasites
por: Voorberg-van der Wel, Annemarie, et al.
Publicado: (2023)

Towards an In Vitro Model of Plasmodium Hypnozoites Suitable for Drug Discovery
por: Dembele, Laurent, et al.
Publicado: (2011)

PI4 Kinase Is a Prophylactic but Not Radical Curative Target in Plasmodium vivax-Type Malaria Parasites
por: Zeeman, Anne-Marie, et al.
Publicado: (2016)

Transcriptomic analysis reveals reduced transcriptional activity in the malaria parasite Plasmodium cynomolgi during progression into dormancy
por: Bertschi, Nicole L, et al.
Publicado: (2018)

K562 erythroleukemia line as a possible reticulocyte source to culture Plasmodium vivax and its surrogates
por: Kronstein-Wiedemann, Romy, et al.
Publicado: (2020)

Transcriptional profiling of hepatocytes infected with the replicative form of the malaria parasite Plasmodium cynomolgi
por: Mitchell, Gabriel, et al.
Publicado: (2022)

Antirelapse Efficacy of Various Primaquine Regimens for Plasmodium vivax
por: Rajgor, D. D., et al.
Publicado: (2014)

High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria
por: Swann, Justine, et al.
Publicado: (2016)

An improved Plasmodium cynomolgi genome assembly reveals an unexpected methyltransferase gene expansion
por: Pasini, Erica M, et al.
Publicado: (2017)

Antimalarial drug discovery: targeting the hypnozoite for new radical curative agent
por: Yeung, Bryan
Publicado: (2012)

Estimation of the Antirelapse Efficacy of Tafenoquine, Using Plasmodium vivax Genotyping
por: Beck, Hans-Peter, et al.
Publicado: (2016)

Plasmodium vivax latent liver infection is characterized by persistent hypnozoites, hypnozoite-derived schizonts, and time-dependent efficacy of primaquine
por: Flannery, Erika L., et al.
Publicado: (2022)

Hypnozoite depletion in successive Plasmodium vivax relapses
por: Noviyanti, Rintis, et al.
Publicado: (2022)

Guidance for Using Tafenoquine for Prevention and Antirelapse Therapy for Malaria — United States, 2019
por: Haston, Julia C., et al.
Publicado: (2019)

Antibody Responses to a Novel Plasmodium falciparum Merozoite Surface Protein Vaccine Correlate with Protection against Experimental Malaria Infection in Aotus Monkeys
por: Cavanagh, David R., et al.
Publicado: (2014)

Superinfection and the hypnozoite reservoir for Plasmodium vivax: a general framework
por: Mehra, Somya, et al.
Publicado: (2023)

Modelling the contribution of the hypnozoite reservoir to Plasmodium vivax transmission
por: White, Michael T, et al.
Publicado: (2014)

A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite Plasmodium cynomolgi
por: Voorberg-van der Wel, Annemarie, et al.
Publicado: (2017)

KAI407, a Potent Non-8-Aminoquinoline Compound That Kills Plasmodium cynomolgi Early Dormant Liver Stage Parasites In Vitro
por: Zeeman, Anne-Marie, et al.
Publicado: (2014)

Modeling the Dynamics of Plasmodium vivax Infection and Hypnozoite Reactivation In Vivo
por: Adekunle, Adeshina I., et al.
Publicado: (2015)

Activation of the hypnozoite: a part of Plasmodium vivax life cycle and survival
por: Hulden, Lena, et al.
Publicado: (2011)

Characterization of the Tubovesicular Network in Plasmodium vivax Liver Stage Hypnozoites and Schizonts
por: Sylvester, Kayla, et al.
Publicado: (2021)

The ethics of using placebo in randomised controlled trials: a case study of a Plasmodium vivax antirelapse trial
por: Cheah, Phaik Yeong, et al.
Publicado: (2018)

A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites
por: Maher, S. P., et al.
Publicado: (2023)

The Plasmodium liver-specific protein 2 (LISP2) is an early marker of liver stage development
por: Gupta, Devendra Kumar, et al.
Publicado: (2019)

Multiple-Clone Activation of Hypnozoites Is the Leading Cause of Relapse in Plasmodium vivax Infection
por: de Araujo, Flávia Carolina F., et al.
Publicado: (2012)

Ethiopian Plasmodium vivax hypnozoites formation dynamics and their susceptibility to reference antimalarial drugs
por: Dembele, Laurent, et al.
Publicado: (2023)

Mass Spectrometry Identification of Biomarkers in Extracellular Vesicles From Plasmodium vivax Liver Hypnozoite Infections
por: Gualdrón-López, Melisa, et al.
Publicado: (2022)

Transfection of the Primate Malaria Parasite Plasmodium knowlesi Using Entirely Heterologous Constructs
por: van der Wel, Anna M., et al.
Publicado: (1997)

Identification of potent and selective N-myristoyltransferase inhibitors of Plasmodium vivax liver stage hypnozoites and schizonts
por: Rodríguez-Hernández, Diego, et al.
Publicado: (2023)

Vaccination with Plasmodium knowlesi AMA1 Formulated in the Novel Adjuvant Co-Vaccine HT™ Protects against Blood-Stage Challenge in Rhesus Macaques
por: Mahdi Abdel Hamid, Muzamil, et al.
Publicado: (2011)

Genetically modified cancer models: the value of luciferase-tagged tumors and in vivo luciferase-based reporter assays in oncology drug discovery
por: Yang, W, et al.
Publicado: (2003)

Hemolytic Dynamics of Weekly Primaquine Antirelapse Therapy Among Cambodians With Acute Plasmodium vivax Malaria With or Without Glucose-6-Phosphate Dehydrogenase Deficiency
por: Taylor, Walter R J, et al.
Publicado: (2019)

Reporter gene comparison demonstrates interference of complex body fluids with secreted luciferase activity
por: Neefjes, M., et al.
Publicado: (2021)

Artemisinin-independent inhibitory activity of Artemisia sp. infusions against different Plasmodium stages including relapse-causing hypnozoites
por: Ashraf, Kutub, et al.
Publicado: (2021)

Corrigendum to: Hemolytic Dynamics of Weekly Primaquine Antirelapse Therapy Among Cambodians With Acute Plasmodium vivax Malaria With or Without Glucose-6-Phosphate Dehydrogenase Deficiency
por: Taylor, Walter R J, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hukfmfdhmtjvjd86bfqcurvbcr