Prolonged Scar-in-a-Jar: an in vitro screening tool for anti-fibrotic therapies using biomarkers of extracellular matrix synthesis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a rapidly progressing disease with challenging management. To find novel effective therapies, better preclinical models are needed for the screening of anti-fibrotic compounds. Activated fibroblasts drive fibrogenesis and are the main cells responsi...

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Detalles Bibliográficos
Autores principales: Rønnow, Sarah Rank, Dabbagh, Rand Qais, Genovese, Federica, Nanthakumar, Carmel B., Barrett, Vikki J., Good, Robert B., Brockbank, Sarah, Cruwys, Simon, Jessen, Henrik, Sorensen, Grith Lykke, Karsdal, Morten Asser, Leeming, Diana Julie, Sand, Jannie Marie Bülow
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203825/
https://www.ncbi.nlm.nih.gov/pubmed/32381012
http://dx.doi.org/10.1186/s12931-020-01369-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203825/
https://www.ncbi.nlm.nih.gov/pubmed/32381012
http://dx.doi.org/10.1186/s12931-020-01369-1

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