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Rho kinase cascade activation in circulating leukocytes in patients with diabetes mellitus type 2

BACKGROUND: The intracellular ROCK signaling pathway is an important modulator of blood pressure and of cardiovascular and renal remodeling when Rho-kinase activity is increased. Besides, in preclinical models of diabetes, ROCK activation has also a role in abnormal glucose metabolism as well as in...

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Detalles Bibliográficos
Autores principales: Ocaranza, Maria Paz, Valderas, Patricio, Moya, Jackeline, Gabrielli, Luigi, Godoy, Iván, Córdova, Samuel, Nab, Paul Mac, García, Lorena, Farías, Luis, Jalil, Jorge E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203835/
https://www.ncbi.nlm.nih.gov/pubmed/32375786
http://dx.doi.org/10.1186/s12933-020-01027-2