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Rho kinase cascade activation in circulating leukocytes in patients with diabetes mellitus type 2
BACKGROUND: The intracellular ROCK signaling pathway is an important modulator of blood pressure and of cardiovascular and renal remodeling when Rho-kinase activity is increased. Besides, in preclinical models of diabetes, ROCK activation has also a role in abnormal glucose metabolism as well as in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203835/ https://www.ncbi.nlm.nih.gov/pubmed/32375786 http://dx.doi.org/10.1186/s12933-020-01027-2 |