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Downregulation of miR-637 promotes vascular smooth muscle cell proliferation and migration via regulation of insulin-like growth factor-2

BACKGROUND: Dysregulation of the proliferation and migration of vascular smooth muscle cells (VSMCs) is a crucial cause of atherosclerosis. MiR-637 exerts an antiproliferative effect on multiple human cells. Its impact on atherosclerosis remains largely unexplored. METHODS: Real-time PCR was used to...

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Detalles Bibliográficos
Autores principales: Yang, Ning, Dong, Bo, Song, Yanqiu, Li, Yang, Kou, Lu, Yang, Jingyu, Qin, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203897/
https://www.ncbi.nlm.nih.gov/pubmed/32399056
http://dx.doi.org/10.1186/s11658-020-00222-z