Molecular Hybrids Integrated with Benzimidazole and Pyrazole Structural Motifs: Design, Synthesis, Biological Evaluation, and Molecular Docking Studies

[Image: see text] Synthesis of a series of benzimidazole-ornamented pyrazoles, 6a–6j has been obtained from arylhydrazine and aralkyl ketones via a multistep synthetic strategy. Among them, a hybrid-possessing para-nitrophenyl moiety connected to a pyrazole scaffold (6a) exerted the highest anti-inf...

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Detalles Bibliográficos
Autores principales: Sivaramakarthikeyan, Ramar, Iniyaval, Shunmugam, Saravanan, Vadivel, Lim, Wei-Meng, Mai, Chun-Wai, Ramalingan, Chennan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203960/
https://www.ncbi.nlm.nih.gov/pubmed/32391496
http://dx.doi.org/10.1021/acsomega.0c00630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203960/
https://www.ncbi.nlm.nih.gov/pubmed/32391496
http://dx.doi.org/10.1021/acsomega.0c00630

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