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Successful treatment of acute B lymphoblastic leukemia relapse in the skin and testicle by anti-CD19 CAR-T with IL-6 knocking down: a case report

BACKGROUND: Extramedullary relapse is an important cause of treatment failure among patients with acute lymphoblastic leukemia (ALL). This type of relapse is commonly observed in the central nervous system, while it is rare in the testicles and skin. Chimeric antigen receptor-modified T cell (CAR-T)...

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Detalles Bibliográficos
Autores principales: Liu, Ze-Fa, Chen, Li-Yun, Wang, Jin, Kang, Li-qing, Tang, Hua, Zhou, Yao, Zhou, Hai-Xia, Sun, Ai-Ning, Wu, De-Pei, Xue, Sheng-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204010/
https://www.ncbi.nlm.nih.gov/pubmed/32399214
http://dx.doi.org/10.1186/s40364-020-00193-5