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Global Transcriptional Profiling Reveals Novel Autocrine Functions of Interleukin 6 in Human Vascular Endothelial Cells

BACKGROUND: Interleukin 6 (IL6) is a multifunctional cytokine produced by various cells, including vascular endothelial cells. IL6 has both pro- and non-/anti-inflammatory functions, and the response to IL6 is dependent on whether it acts via the membrane-bound IL6 receptor α (IL6Rα) (classic signal...

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Detalles Bibliográficos
Autores principales: Ljungberg, Liza U., Zegeye, Mulugeta M., Kardeby, Caroline, Fälker, Knut, Repsilber, Dirk, Sirsjö, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204122/
https://www.ncbi.nlm.nih.gov/pubmed/32410854
http://dx.doi.org/10.1155/2020/4623107