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Graphing and reporting heterogeneous treatment effects through reference classes

BACKGROUND: Exploration and modelling of heterogeneous treatment effects as a function of baseline covariates is an important aspect of precision medicine in randomised controlled trials (RCTs). Randomisation generally guarantees the internal validity of an RCT, but heterogeneity in treatment effect...

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Detalles Bibliográficos
Autores principales: Watson, James A., Holmes, Chris C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204233/
https://www.ncbi.nlm.nih.gov/pubmed/32381030
http://dx.doi.org/10.1186/s13063-020-04306-1