Evaluation of survival extrapolation in immuno-oncology using multiple pre-planned data cuts: learnings to aid in model selection

BACKGROUND: Due to limited duration of follow up in clinical trials of cancer treatments, estimates of lifetime survival benefits are typically derived using statistical extrapolation methods. To justify the method used, a range of approaches have been proposed including statistical goodness-of-fit...

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Detalles Bibliográficos
Autores principales: Bullement, Ash, Willis, Anna, Amin, Amerah, Schlichting, Michael, Hatswell, Anthony James, Bharmal, Murtuza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204248/
https://www.ncbi.nlm.nih.gov/pubmed/32375680
http://dx.doi.org/10.1186/s12874-020-00997-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204248/
https://www.ncbi.nlm.nih.gov/pubmed/32375680
http://dx.doi.org/10.1186/s12874-020-00997-x

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