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Analysis of the F2LR3 (PAR4) Single Nucleotide Polymorphism (rs773902) in an Indigenous Australian Population

The F2RL3 gene encoding protease activated receptor 4 (PAR4) contains a single nucleotide variant, rs773902, that is functional. The resulting PAR4 variants, Thr120, and Ala120, are known to differently affect platelet reactivity to thrombin. Significant population differences in the frequency of th...

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Detalles Bibliográficos
Autores principales: Ningtyas, Dian, Thomson, Russell J., Tarlac, Volga, Nagaraj, Shivashankar H., Hoy, Wendy, Mathews, John D., Foote, Simon J., Gardiner, Elizabeth E., Hamilton, Justin R., McMorran, Brendan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204273/
https://www.ncbi.nlm.nih.gov/pubmed/32425989
http://dx.doi.org/10.3389/fgene.2020.00432