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Chromosomal instability in untreated primary prostate cancer as an indicator of metastatic potential

BACKGROUND: Metastatic prostate cancer (PC) is highly lethal. The ability to identify primary tumors capable of dissemination is an unmet need in the quest to understand lethal biology and improve patient outcomes. Previous studies have linked chromosomal instability (CIN), which generates aneuploid...

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Detalles Bibliográficos
Autores principales: Miller, Eric T., You, Sungyong, Cadaneanu, Radu M., Kim, Minhyung, Yoon, Junhee, Liu, Sandy T., Li, Xinmin, Kwan, Lorna, Hodge, Jennelle, Quist, Michael J., Grasso, Catherine S., Lewis, Michael S., Knudsen, Beatrice S., Freeman, Michael R., Garraway, Isla P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204307/
https://www.ncbi.nlm.nih.gov/pubmed/32380981
http://dx.doi.org/10.1186/s12885-020-06817-1