Comprehensive dissection of dispensable genomic regions in Streptomyces based on comparative analysis approach

BACKGROUND: Large-scale genome reduction has been performed to significantly improve the performance of microbial chassis. Identification of the essential or dispensable genes is pivotal for genome reduction to avoid synthetic lethality. Here, taking Streptomyces as an example, we developed a combin...

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Detalles Bibliográficos
Autores principales: Bu, Qing-Ting, Li, Yue-Ping, Xie, Huang, Wang, Jue, Li, Zi-Yue, Chen, Xin-Ai, Mao, Xu-Ming, Li, Yong-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204314/
https://www.ncbi.nlm.nih.gov/pubmed/32375781
http://dx.doi.org/10.1186/s12934-020-01359-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204314/
https://www.ncbi.nlm.nih.gov/pubmed/32375781
http://dx.doi.org/10.1186/s12934-020-01359-4

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