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Comprehensive dissection of dispensable genomic regions in Streptomyces based on comparative analysis approach
BACKGROUND: Large-scale genome reduction has been performed to significantly improve the performance of microbial chassis. Identification of the essential or dispensable genes is pivotal for genome reduction to avoid synthetic lethality. Here, taking Streptomyces as an example, we developed a combin...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204314/ https://www.ncbi.nlm.nih.gov/pubmed/32375781 http://dx.doi.org/10.1186/s12934-020-01359-4 |