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Sequential formation of different layers of dystrophic neurites in Alzheimer’s brains

Alzheimer’s disease (AD) is characterized by the presence of neuritic plaques in which dystrophic neurites (DNs) are typical constituents. We recently showed that DNs labeled by antibodies to the tubular endoplasmic reticulum (ER) protein reticulon-3 (RTN3) are enriched with clustered tubular ER. Ho...

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Detalles Bibliográficos
Autores principales: Sharoar, Md Golam, Hu, Xiangyou, Ma, Xin-Ming, Zhu, Xiongwei, Yan, Riqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204504/
https://www.ncbi.nlm.nih.gov/pubmed/30899091
http://dx.doi.org/10.1038/s41380-019-0396-2