A Case of Tyrosine Kinase Inhibitor-Resistant Chronic Myeloid Leukemia, Chronic Phase with ASXL1 Mutation

Hematological malignancies, including chronic myeloid leukemia (CML), exhibit ASXL1 mutations; however, the function and molecular mechanism of these mutations remain unclear. ASXL1 was originally identified as tumor suppressor gene, in which loss of function causes myelodysplastic syndrome (MDS). A...

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Detalles Bibliográficos
Autores principales: Imataki, Osamu, Ishida, Tomoya, Kubo, Hiroyuki, Uemura, Makiko, Nanya, Yasuhito, Kawakami, Kimihiro, Ogawa, Seishi, Kadowaki, Norimitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204851/
https://www.ncbi.nlm.nih.gov/pubmed/32399015
http://dx.doi.org/10.1159/000506452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204851/
https://www.ncbi.nlm.nih.gov/pubmed/32399015
http://dx.doi.org/10.1159/000506452

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