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Targeting the Small GTPase Superfamily through Their Regulatory Proteins
The Ras superfamily of small GTPases are guanine‐nucleotide‐dependent switches essential for numerous cellular processes. Mutations or dysregulation of these proteins are associated with many diseases, but unsuccessful attempts to target the small GTPases directly have resulted in them being classed...
Autores principales: | Gray, Janine L., von Delft, Frank, Brennan, Paul E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204875/ https://www.ncbi.nlm.nih.gov/pubmed/30869179 http://dx.doi.org/10.1002/anie.201900585 |
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