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Correcting Task fMRI Signals for Variability in Baseline CBF Improves BOLD-Behavior Relationships: A Feasibility Study in an Aging Model

Blood Oxygen Level Dependent (BOLD) functional MRI is a complex neurovascular signal whose magnitude depends on baseline physiological factors such as cerebral blood flow (CBF). Because baseline CBF varies across the brain and is altered with aging, the interpretation of stand-alone aging-related BO...

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Detalles Bibliográficos
Autores principales: Krishnamurthy, Venkatagiri, Krishnamurthy, Lisa C., Drucker, Jonathan H., Kundu, Suprateek, Ji, Bing, Hortman, Kyle, Roberts, Simone R., Mammino, Kevin, Tran, Stella M., Gopinath, Kaundinya, McGregor, Keith M., Rodriguez, Amy D., Qiu, Deqiang, Crosson, Bruce, Nocera, Joe R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205008/
https://www.ncbi.nlm.nih.gov/pubmed/32425745
http://dx.doi.org/10.3389/fnins.2020.00336