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Crystal structure of the mitochondrial protein mitoNEET bound to a benze-sulfonide ligand

MitoNEET (gene cisd1) is a mitochondrial outer membrane [2Fe-2S] protein and is a potential drug target in several metabolic diseases. Previous studies have demonstrated that mitoNEET functions as a redox-active and pH-sensing protein that regulates mitochondrial metabolism, although the structural...

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Detalles Bibliográficos
Autores principales: Geldenhuys, Werner J., Long, Timothy E., Saralkar, Pushkar, Iwasaki, Toshio, Nuñez, Raisa A.A., Nair, Rajesh R., Konkle, Mary E., Menze, Michael A., Pinti, Mark V., Hollander, John M., Hazlehurst, Lori A., Robart, Aaron R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205193/
https://www.ncbi.nlm.nih.gov/pubmed/32382661
http://dx.doi.org/10.1038/s42004-019-0172-x