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Crystal structure of the mitochondrial protein mitoNEET bound to a benze-sulfonide ligand
MitoNEET (gene cisd1) is a mitochondrial outer membrane [2Fe-2S] protein and is a potential drug target in several metabolic diseases. Previous studies have demonstrated that mitoNEET functions as a redox-active and pH-sensing protein that regulates mitochondrial metabolism, although the structural...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205193/ https://www.ncbi.nlm.nih.gov/pubmed/32382661 http://dx.doi.org/10.1038/s42004-019-0172-x |