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High-yield production of recombinant platelet factor 4 by harnessing and honing the gram-negative bacterial secretory apparatus

Platelet factor 4 is a cytokine released into the bloodstream by activated platelets where it plays a pivotal role in etiology and diagnosis of heparin-induced thrombocytopenia. Therefore, a sustainable source of recombinant PF4 with structural and functional similarity to its native form is urgentl...

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Detalles Bibliográficos
Autores principales: Ataei, Saeed, Taheri, Mohammad Naser, Tamaddon, Gholamhossein, Behzad-Behbahani, Abbas, Taheri, Fatemeh, Rahimi, Amir, Zare, Farahnaz, Amirian, Niloofar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205247/
https://www.ncbi.nlm.nih.gov/pubmed/32379796
http://dx.doi.org/10.1371/journal.pone.0232661