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Hyd ubiquitinates the NF-κB co-factor Akirin to operate an effective immune response in Drosophila
The Immune Deficiency (IMD) pathway in Drosophila melanogaster is activated upon microbial challenge with Gram-negative bacteria to trigger the innate immune response. In order to decipher this nuclear factor κB (NF-κB) signaling pathway, we undertook an in vitro RNAi screen targeting E3 ubiquitin l...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205318/ https://www.ncbi.nlm.nih.gov/pubmed/32339205 http://dx.doi.org/10.1371/journal.ppat.1008458 |