Indomethacin attenuates mechanical allodynia during the organization but not the maintenance of the peripheral neuropathic pain induced by nervus ischiadicus chronic constriction injury

The neurochemical mechanisms underlying neuropathic pain (NP) are related to peripheral and central sensitization caused by the release of inflammatory mediators in the peripheral damaged tissue and ectopic discharges from the injured nerve, leading to a hyperexcitable state of spinal dorsal horn ne...

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Detalles Bibliográficos
Autores principales: Medeiros, P., dos Santos, I.R., Medeiros, A.C., da Silva, J.A., Ferreira, S.H., de Freitas, R.L., Coimbra, N.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205414/
https://www.ncbi.nlm.nih.gov/pubmed/32348427
http://dx.doi.org/10.1590/1414-431X20209255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205414/
https://www.ncbi.nlm.nih.gov/pubmed/32348427
http://dx.doi.org/10.1590/1414-431X20209255

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