Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium

The IL1RL1 (ST2) gene locus is robustly associated with asthma; however, the contribution of single nucleotide polymorphisms (SNPs) in this locus to specific asthma subtypes and the functional mechanisms underlying these associations remain to be defined. We tested for association between IL1RL1 reg...

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Detalles Bibliográficos
Autores principales: Portelli, Michael A., Dijk, F. Nicole, Ketelaar, Maria E., Shrine, Nick, Hankinson, Jenny, Bhaker, Sangita, Grotenboer, Néomi S., Obeidat, Ma’en, Henry, Amanda P., Billington, Charlotte K., Shaw, Dominick, Johnson, Simon R., Pogson, Zara E.K., Fogarty, Andrew, McKeever, Tricia M., Nickle, David C., Bossé, Yohan, van den Berge, Maarten, Faiz, Alen, Brouwer, Sharon, Vonk, Judith M., de Vos, Paul, Brandsma, Corry-Anke, Vermeulen, Cornelis J., Singapuri, Amisha, Heaney, Liam G., Mansur, Adel H., Chaudhuri, Rekha, Thomson, Neil C., Holloway, John W., Lockett, Gabrielle A., Howarth, Peter H., Niven, Robert, Simpson, Angela, Blakey, John D., Tobin, Martin D., Postma, Dirkje S., Hall, Ian P., Wain, Louise V., Nawijn, Martijn C., Brightling, Christopher E., Koppelman, Gerard H., Sayers, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205441/
https://www.ncbi.nlm.nih.gov/pubmed/32324168
http://dx.doi.org/10.1172/jci.insight.132446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205441/
https://www.ncbi.nlm.nih.gov/pubmed/32324168
http://dx.doi.org/10.1172/jci.insight.132446

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