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A single power stroke by ATP binding drives substrate translocation in a heterodimeric ABC transporter

ATP-binding cassette (ABC) transporters constitute the largest family of primary active transporters, responsible for many physiological processes and human maladies. However, the mechanism how chemical energy of ATP facilitates translocation of chemically diverse compounds across membranes is poorl...

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Detalles Bibliográficos
Autores principales: Stefan, Erich, Hofmann, Susanne, Tampé, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205462/
https://www.ncbi.nlm.nih.gov/pubmed/32314962
http://dx.doi.org/10.7554/eLife.55943