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A single power stroke by ATP binding drives substrate translocation in a heterodimeric ABC transporter
ATP-binding cassette (ABC) transporters constitute the largest family of primary active transporters, responsible for many physiological processes and human maladies. However, the mechanism how chemical energy of ATP facilitates translocation of chemically diverse compounds across membranes is poorl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205462/ https://www.ncbi.nlm.nih.gov/pubmed/32314962 http://dx.doi.org/10.7554/eLife.55943 |