Diversity in kinetics correlated with structure in nano body-stabilized LacY

The structure of lactose permease, stabilized in a periplasmic open conformation by two Gly to Trp replacements (LacYww) and complexed with a nanobody directed against this conformation, provides the highest resolution structure of the symporter. The nanobody binds in a different manner than two oth...

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Detalles Bibliográficos
Autores principales: Kumar, Hemant, Finer-Moore, Janet, Smirnova, Irina, Kasho, Vladimir, Pardon, Els, Steyaert, Jan, Kaback, H. Ronald, Stroud, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205474/
https://www.ncbi.nlm.nih.gov/pubmed/32380514
http://dx.doi.org/10.1371/journal.pone.0232846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205474/
https://www.ncbi.nlm.nih.gov/pubmed/32380514
http://dx.doi.org/10.1371/journal.pone.0232846

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