Two Functional Fatty Acyl Coenzyme A Ligases Affect Free Fatty Acid Metabolism To Block Biosynthesis of an Antifungal Antibiotic in Lysobacter enzymogenes

In Lysobacter enzymogenes OH11, RpfB1 and RpfB2 were predicted to encode acyl coenzyme A (CoA) ligases. RpfB1 is located in the Rpf gene cluster. Interestingly, we found an RpfB1 homolog (RpfB2) outside this canonical gene cluster, and nothing is known about its functionality or mechanism. Here, we...

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Detalles Bibliográficos
Autores principales: Li, Kaihuai, Hou, Rongxian, Xu, Huiyong, Wu, Guichun, Qian, Guoliang, Wang, Haihong, Liu, Fengquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Environmental Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205486/
https://www.ncbi.nlm.nih.gov/pubmed/32144106
http://dx.doi.org/10.1128/AEM.00309-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205486/
https://www.ncbi.nlm.nih.gov/pubmed/32144106
http://dx.doi.org/10.1128/AEM.00309-20

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