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Single-molecule displacement mapping unveils nanoscale heterogeneities in intracellular diffusivity

Intracellular diffusion underlies vital cellular processes. However, it remains difficult to elucidate how an unbound protein diffuses inside the cell with good spatial resolution and sensitivity. Here we introduce single-molecule displacement/diffusivity mapping (SMdM), a super-resolution strategy...

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Detalles Bibliográficos
Autores principales: Xiang, Limin, Chen, Kun, Yan, Rui, Li, Wan, Xu, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205592/
https://www.ncbi.nlm.nih.gov/pubmed/32203387
http://dx.doi.org/10.1038/s41592-020-0793-0