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Single-molecule displacement mapping unveils nanoscale heterogeneities in intracellular diffusivity
Intracellular diffusion underlies vital cellular processes. However, it remains difficult to elucidate how an unbound protein diffuses inside the cell with good spatial resolution and sensitivity. Here we introduce single-molecule displacement/diffusivity mapping (SMdM), a super-resolution strategy...
Autores principales: | Xiang, Limin, Chen, Kun, Yan, Rui, Li, Wan, Xu, Ke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205592/ https://www.ncbi.nlm.nih.gov/pubmed/32203387 http://dx.doi.org/10.1038/s41592-020-0793-0 |
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