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Triple combination therapy of favipiravir plus two monoclonal antibodies eradicates influenza virus from nude mice

Prolonged treatment of immunocompromised influenza patients with viral neuraminidase (NA) inhibitors is required, because the immune system of such patients fails to eradicate the viruses. Here, we attempted to eradicate influenza virus from the respiratory organs of nude mice, which is a model of i...

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Detalles Bibliográficos
Autores principales: Kiso, Maki, Yamayoshi, Seiya, Kawaoka, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205604/
https://www.ncbi.nlm.nih.gov/pubmed/32382088
http://dx.doi.org/10.1038/s42003-020-0952-y