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Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism

Mycobacterium tuberculosis (Mtb) encodes an exceptionally large number of toxin-antitoxin (TA) systems, supporting the hypothesis that TA systems are involved in pathogenesis. We characterized the putative Mtb Rv1044-Rv1045 TA locus structurally and functionally, demonstrating that it constitutes a...

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Detalles Bibliográficos
Autores principales:	Yu, Xia, Gao, Xiaopan, Zhu, Kaixiang, Yin, Han, Mao, Xujian, Wojdyla, Justyna Aleksandra, Qin, Bo, Huang, Hairong, Wang, Meitian, Sun, Yi-Cheng, Cui, Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205606/ https://www.ncbi.nlm.nih.gov/pubmed/32382148 http://dx.doi.org/10.1038/s42003-020-0941-1

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