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Hsa_circ_0079662 induces the resistance mechanism of the chemotherapy drug oxaliplatin through the TNF‐α pathway in human colon cancer

The aim of the study was to research the biological functions of circRNA (hsa_circ_0079662) and its underlying mechanism in colorectal cancer. Drug‐resistant cell lines (HT29‐LOHP, HCT116‐LOHP, HCT8‐LOHP) were separately dealt with oxaliplatin concentration gradient (0.1‐10 μmol/L). Real‐time PCR, W...

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Detalles Bibliográficos
Autores principales: Lai, Mingfen, Liu, Guiju, Li, Ruijun, Bai, Hua, Zhao, Jizhi, Xiao, Peng, Mei, Jiazhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205783/
https://www.ncbi.nlm.nih.gov/pubmed/32243061
http://dx.doi.org/10.1111/jcmm.15122